Loading...
Benzimidazole-2-one: A Novel Anchoring Principle For Antagonizing p53-Mdm2
Herein we propose the benzimidazole-2-one substructure as a suitable tryptophan mimic and thus a reasonable starting point for the design of p53 Mdm2 antagonists. We devise a short multicomponent reaction route to hitherto unknown 2-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamides by reacting...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3716288/ https://ncbi.nlm.nih.gov/pubmed/22789708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.06.020 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|