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The Structure-Based Design of Mdm2/Mdmx–p53 Inhibitors Gets Serious
The p53 protein is the cell’s principal bastion of defense against tumor-associated DNA damage. Commonly referred as a “guardian of the genome”, p53 is responsible for determining the fate of the cell when the integrity of its genome is damaged. The development of tumors requires breaching this defe...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2011
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3113661/ https://ncbi.nlm.nih.gov/pubmed/21341346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201003863 |
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