Lataa...
Benzimidazole-2-one: A Novel Anchoring Principle For Antagonizing p53-Mdm2
Herein we propose the benzimidazole-2-one substructure as a suitable tryptophan mimic and thus a reasonable starting point for the design of p53 Mdm2 antagonists. We devise a short multicomponent reaction route to hitherto unknown 2-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamides by reacting...
Tallennettuna:
| Päätekijät: | , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2012
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3716288/ https://ncbi.nlm.nih.gov/pubmed/22789708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.06.020 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|