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The Brn-2 Transcription Factor Links Activated BRAF to Melanoma Proliferation
Malignant melanoma, an aggressive and increasingly common cancer, is characterized by a strikingly high rate (70%) of mutations in BRAF, a key component of the mitogen-activated protein (MAP) kinase signaling pathway. How signaling events downstream from BRAF affect the underlying program of gene ex...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC371133/ https://ncbi.nlm.nih.gov/pubmed/15024080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.7.2923-2931.2004 |
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