Φορτώνει......
Elevated expression of MITF counteracts B-RAF–stimulated melanocyte and melanoma cell proliferation
The protein kinase B-RAF is a human oncogene that is mutated in ∼70% of human melanomas and transforms mouse melanocytes. Microphthalmia-associated transcription factor (MITF) is an important melanocyte differentiation and survival factor, but its role in melanoma is unclear. In this study, we show...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The Rockefeller University Press
2005
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2171350/ https://ncbi.nlm.nih.gov/pubmed/16129781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200505059 |
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