Oncogenic BRAF Regulates Melanoma Proliferation through the Lineage Specific Factor MITF

The Microphthalmia-associated transcription factor (MITF) is an important regulator of cell-type specific functions in melanocytic cells. MITF is essential for the survival of pigmented cells, but whereas high levels of MITF drive melanocyte differentiation, lower levels are required to permit proli...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wellbrock, Claudia, Rana, Sareena, Paterson, Hugh, Pickersgill, Helen, Brummelkamp, Thijn, Marais, Richard
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2008
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2444043/
https://ncbi.nlm.nih.gov/pubmed/18628967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002734
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