Llwytho...

Cloning and sequencing of the kedarcidin biosynthetic gene cluster from Streptoalloteichus sp. ATCC 53650 revealing new insights into biosynthesis of the enediyne family of antitumor antibiotics()

Enediyne natural product biosynthesis is characterized by a convergence of multiple pathways, generating unique peripheral moieties that are appended onto the distinctive enediyne core. Kedarcidin (KED) possesses two unique peripheral moieties, a (R)-2-aza-3-chloro-β-tyrosine and an iso-propoxy-bear...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lohman, Jeremy R., Huang, Sheng-Xiong, Horsman, Geoffrey P., Dilfer, Paul E., Huang, Tingting, Chen, Yihua, Wendt-Pienkowski, Evelyn, Shen, Ben
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711097/
https://ncbi.nlm.nih.gov/pubmed/23360970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3mb25523a
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