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Structure of the human cohesin inhibitor Wapl
Cohesin, along with positive regulators, establishes sister-chromatid cohesion by forming a ring to circle chromatin. The wings apart-like protein (Wapl) is a key negative regulator of cohesin and forms a complex with precocious dissociation of sisters protein 5 (Pds5) to promote cohesin release fro...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3710786/ https://ncbi.nlm.nih.gov/pubmed/23776203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304594110 |
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