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Structure of the human cohesin inhibitor Wapl

Cohesin, along with positive regulators, establishes sister-chromatid cohesion by forming a ring to circle chromatin. The wings apart-like protein (Wapl) is a key negative regulator of cohesin and forms a complex with precocious dissociation of sisters protein 5 (Pds5) to promote cohesin release fro...

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Detalhes bibliográficos
Main Authors: Ouyang, Zhuqing, Zheng, Ge, Song, Jianhua, Borek, Dominika M., Otwinowski, Zbyszek, Brautigam, Chad A., Tomchick, Diana R., Rankin, Susannah, Yu, Hongtao
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710786/
https://ncbi.nlm.nih.gov/pubmed/23776203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304594110
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