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Structural Basis and IP(6) Requirement for Pds5-dependent Cohesin Dynamics

The ring-shaped cohesin complex regulates transcription, DNA repair, and chromosome segregation by dynamically entrapping chromosomes to promote chromosome compaction and sister-chromatid cohesion. The cohesin ring needs to open and close to allow its loading to and release from chromosomes. Cohesin...

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Bibliographic Details
Published in:Mol Cell
Main Authors: Ouyang, Zhuqing, Zheng, Ge, Tomchick, Diana R., Luo, Xuelian, Yu, Hongtao
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560056/
https://ncbi.nlm.nih.gov/pubmed/26971492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.02.033
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