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Structure of cohesin subcomplex pinpoints direct shugoshin–Wapl antagonism in centromeric cohesion
Orderly termination of sister-chromatid cohesion during mitosis is critical for accurate chromosome segregation. During prophase, mitotic kinases phosphorylate cohesin and its protector sororin, triggering Wapl-dependent cohesin release from chromosome arms. The shugoshin (Sgo1)–PP2A complex protect...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4190070/ https://ncbi.nlm.nih.gov/pubmed/25173175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2880 |
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