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A kinase‐dependent role for Haspin in antagonizing Wapl and protecting mitotic centromere cohesion
Sister‐chromatid cohesion mediated by the cohesin complex is fundamental for precise chromosome segregation in mitosis. Through binding the cohesin subunit Pds5, Wapl releases the bulk of cohesin from chromosome arms in prophase, whereas centromeric cohesin is protected from Wapl until anaphase onse...
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| Yayımlandı: | EMBO Rep |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
John Wiley and Sons Inc.
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5757254/ https://ncbi.nlm.nih.gov/pubmed/29138236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744737 |
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