A kinase‐dependent role for Haspin in antagonizing Wapl and protecting mitotic centromere cohesion

Sister‐chromatid cohesion mediated by the cohesin complex is fundamental for precise chromosome segregation in mitosis. Through binding the cohesin subunit Pds5, Wapl releases the bulk of cohesin from chromosome arms in prophase, whereas centromeric cohesin is protected from Wapl until anaphase onse...

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Bibliografiske detaljer
Udgivet i:EMBO Rep
Main Authors: Liang, Cai, Chen, Qinfu, Yi, Qi, Zhang, Miao, Yan, Haiyan, Zhang, Bo, Zhou, Linli, Zhang, Zhenlei, Qi, Feifei, Ye, Sheng, Wang, Fangwei
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Scientific Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757254/
https://ncbi.nlm.nih.gov/pubmed/29138236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744737
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