Cohesin-interacting protein WAPL-1 regulates meiotic chromosome structure and cohesion by antagonizing specific cohesin complexes

Wapl induces cohesin dissociation from DNA throughout the mitotic cell cycle, modulating sister chromatid cohesion and higher-order chromatin structure. Cohesin complexes containing meiosis-specific kleisin subunits govern most aspects of meiotic chromosome function, but whether Wapl regulates these...

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Bibliographic Details
Published in:eLife
Main Authors: Crawley, Oliver, Barroso, Consuelo, Testori, Sarah, Ferrandiz, Nuria, Silva, Nicola, Castellano-Pozo, Maikel, Jaso-Tamame, Angel Luis, Martinez-Perez, Enrique
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2016
Subjects:
Genes and Chromosomes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758955/
https://ncbi.nlm.nih.gov/pubmed/26841696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10851
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