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Wapl antagonizes cohesin binding and promotes Polycomb-group silencing in Drosophila
Wapl protein regulates binding of the cohesin complex to chromosomes during interphase and helps remove cohesin from chromosomes at mitosis. We isolated a dominant mutation in wapl (wapl(AG)) in a screen for mutations that counteract silencing mediated by an engrailed Polycomb-group response element...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3478686/ https://ncbi.nlm.nih.gov/pubmed/23034634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.084566 |
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