Wapl antagonizes cohesin binding and promotes Polycomb-group silencing in Drosophila

Wapl protein regulates binding of the cohesin complex to chromosomes during interphase and helps remove cohesin from chromosomes at mitosis. We isolated a dominant mutation in wapl (wapl(AG)) in a screen for mutations that counteract silencing mediated by an engrailed Polycomb-group response element...

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Bibliografske podrobnosti
Main Authors: Cunningham, Melissa D., Gause, Maria, Cheng, Yuzhong, Noyes, Amanda, Dorsett, Dale, Kennison, James A., Kassis, Judith A
Format: Artigo
Jezik:Inglês
Izdano: Company of Biologists 2012
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478686/
https://ncbi.nlm.nih.gov/pubmed/23034634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.084566
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