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Pds5 promotes cohesin acetylation and stable cohesin–chromosome interaction

Pds5 and Wpl1 act as anti-establishment factors preventing sister-chromatid cohesion until counteracted in S-phase by the cohesin acetyl-transferase Eso1. However, Pds5 is also required to maintain sister-chromatid cohesion in G2. Here, we show that Pds5 is essential for cohesin acetylation by Eso1...

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Autors principals: Vaur, Sabine, Feytout, Amélie, Vazquez, Stéphanie, Javerzat, Jean-Paul
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388792/
https://ncbi.nlm.nih.gov/pubmed/22640989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.72
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