The CDK Pef1 and protein phosphatase 4 oppose each other for regulating cohesin binding to fission yeast chromosomes

Cohesin has essential roles in chromosome structure, segregation and repair. Cohesin binding to chromosomes is catalyzed by the cohesin loader, Mis4 in fission yeast. How cells fine tune cohesin deposition is largely unknown. Here, we provide evidence that Mis4 activity is regulated by phosphorylati...

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Bibliografski detalji
Izdano u:eLife
Glavni autori: Birot, Adrien, Tormos-Pérez, Marta, Vaur, Sabine, Feytout, Amélie, Jaegy, Julien, Alonso Gil, Dácil, Vazquez, Stéphanie, Ekwall, Karl, Javerzat, Jean-Paul
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2020
Teme:
Chromosomes and Gene Expression
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954021/
https://ncbi.nlm.nih.gov/pubmed/31895039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50556
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