The CDK Pef1 and protein phosphatase 4 oppose each other for regulating cohesin binding to fission yeast chromosomes

Cohesin has essential roles in chromosome structure, segregation and repair. Cohesin binding to chromosomes is catalyzed by the cohesin loader, Mis4 in fission yeast. How cells fine tune cohesin deposition is largely unknown. Here, we provide evidence that Mis4 activity is regulated by phosphorylati...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Birot, Adrien, Tormos-Pérez, Marta, Vaur, Sabine, Feytout, Amélie, Jaegy, Julien, Alonso Gil, Dácil, Vazquez, Stéphanie, Ekwall, Karl, Javerzat, Jean-Paul
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Chromosomes and Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954021/
https://ncbi.nlm.nih.gov/pubmed/31895039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50556
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