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Structural basis of cohesin cleavage by separase

Accurate chromosome segregation requires timely dissolution of chromosome cohesion after chromosomes are properly attached to the mitotic spindle. Separase is absolutely essential for cohesion dissolution in organisms from yeast to man(1,2). It cleaves the kleisin subunit of cohesin and opens the co...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Lin, Zhonghui, Luo, Xuelian, Yu, Hongtao
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847710/
https://ncbi.nlm.nih.gov/pubmed/27027290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17402
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