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Structural basis of cohesin cleavage by separase

Accurate chromosome segregation requires timely dissolution of chromosome cohesion after chromosomes are properly attached to the mitotic spindle. Separase is absolutely essential for cohesion dissolution in organisms from yeast to man(1,2). It cleaves the kleisin subunit of cohesin and opens the co...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nature
Egile Nagusiak: Lin, Zhonghui, Luo, Xuelian, Yu, Hongtao
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847710/
https://ncbi.nlm.nih.gov/pubmed/27027290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17402
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