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Structural basis of cohesin cleavage by separase
Accurate chromosome segregation requires timely dissolution of chromosome cohesion after chromosomes are properly attached to the mitotic spindle. Separase is absolutely essential for cohesion dissolution in organisms from yeast to man(1,2). It cleaves the kleisin subunit of cohesin and opens the co...
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| 發表在: | Nature |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4847710/ https://ncbi.nlm.nih.gov/pubmed/27027290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17402 |
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