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Structural basis of cohesin cleavage by separase

Accurate chromosome segregation requires timely dissolution of chromosome cohesion after chromosomes are properly attached to the mitotic spindle. Separase is absolutely essential for cohesion dissolution in organisms from yeast to man(1,2). It cleaves the kleisin subunit of cohesin and opens the co...

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Dades bibliogràfiques
Publicat a:Nature
Autors principals: Lin, Zhonghui, Luo, Xuelian, Yu, Hongtao
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847710/
https://ncbi.nlm.nih.gov/pubmed/27027290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17402
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