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Structural basis of cohesin cleavage by separase
Accurate chromosome segregation requires timely dissolution of chromosome cohesion after chromosomes are properly attached to the mitotic spindle. Separase is absolutely essential for cohesion dissolution in organisms from yeast to man(1,2). It cleaves the kleisin subunit of cohesin and opens the co...
Salvato in:
| Pubblicato in: | Nature |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4847710/ https://ncbi.nlm.nih.gov/pubmed/27027290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17402 |
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