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Cohesin Acetylation Promotes Sister Chromatid Cohesion Only in Association with the Replication Machinery
Acetylation of the Smc3 subunit of cohesin is essential to establish functional cohesion between sister chromatids. Smc3 acetylation is catalyzed by members of the Eco family of acetyltransferases, although the mechanism by which acetylation is regulated and how it promotes cohesion are largely unkn...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3464539/ https://ncbi.nlm.nih.gov/pubmed/22896698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.400192 |
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