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Multivalent interaction of ESCO2 with the replication machinery is required for sister chromatid cohesion in vertebrates

The tethering together of sister chromatids by the cohesin complex ensures their accurate alignment and segregation during cell division. In vertebrates, sister chromatid cohesion requires the activity of the ESCO2 acetyltransferase, which modifies the Smc3 subunit of cohesin. It was shown recently...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bender, Dawn, Da Silva, Eulália Maria Lima, Chen, Jingrong, Poss, Annelise, Gawey, Lauren, Rulon, Zane, Rankin, Susannah
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6969535/
https://ncbi.nlm.nih.gov/pubmed/31879348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911936117
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