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Multivalent interaction of ESCO2 with the replication machinery is required for sister chromatid cohesion in vertebrates
The tethering together of sister chromatids by the cohesin complex ensures their accurate alignment and segregation during cell division. In vertebrates, sister chromatid cohesion requires the activity of the ESCO2 acetyltransferase, which modifies the Smc3 subunit of cohesin. It was shown recently...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6969535/ https://ncbi.nlm.nih.gov/pubmed/31879348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911936117 |
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