The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion

Chromosome segregation depends on sister chromatid cohesion which is established by cohesin during DNA replication. Cohesive cohesin complexes become acetylated to prevent their precocious release by WAPL before cells have reached mitosis. To obtain insight into how DNA replication, cohesion establi...

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Vydáno v:EMBO J
Hlavní autoři: Ivanov, Miroslav P, Ladurner, Rene, Poser, Ina, Beveridge, Rebecca, Rampler, Evelyn, Hudecz, Otto, Novatchkova, Maria, Hériché, Jean‐Karim, Wutz, Gordana, van der Lelij, Petra, Kreidl, Emanuel, Hutchins, James RA, Axelsson‐Ekker, Heinz, Ellenberg, Jan, Hyman, Anthony A, Mechtler, Karl, Peters, Jan‐Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068434/
https://ncbi.nlm.nih.gov/pubmed/29930102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797150
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