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Cohesin Acetylation Promotes Sister Chromatid Cohesion Only in Association with the Replication Machinery

Acetylation of the Smc3 subunit of cohesin is essential to establish functional cohesion between sister chromatids. Smc3 acetylation is catalyzed by members of the Eco family of acetyltransferases, although the mechanism by which acetylation is regulated and how it promotes cohesion are largely unkn...

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Auteurs principaux: Song, Jianhua, Lafont, Andrea, Chen, Jingrong, Wu, Frank M., Shirahige, Katsuhiko, Rankin, Susannah
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464539/
https://ncbi.nlm.nih.gov/pubmed/22896698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.400192
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