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Crystal structure of the cohesin loader Scc2 and insight into cohesinopathy

The ring-shaped cohesin complex topologically entraps chromosomes and regulates chromosome segregation, transcription, and DNA repair. The cohesin core consists of the structural maintenance of chromosomes 1 and 3 (Smc1–Smc3) heterodimeric ATPase, the kleisin subunit sister chromatid cohesion 1 (Scc...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Kikuchi, Sotaro, Borek, Dominika M., Otwinowski, Zbyszek, Tomchick, Diana R., Yu, Hongtao
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098657/
https://ncbi.nlm.nih.gov/pubmed/27791135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611333113
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