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Crystal Structure of the Cohesin Gatekeeper Pds5 and in Complex with Kleisin Scc1

Sister chromatid cohesion is mediated by cohesin, whose Smc1, Smc3, and kleisin (Scc1) subunits form a ring structure that entraps sister DNAs. The ring is opened either by separase, which cleaves Scc1 during anaphase, or by a releasing activity involving Wapl, Scc3, and Pds5, which bind to Scc1 and...

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Bibliografski detalji
Izdano u:Cell Rep
Glavni autori: Lee, Byung-Gil, Roig, Maurici B., Jansma, Marijke, Petela, Naomi, Metson, Jean, Nasmyth, Kim, Löwe, Jan
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2016
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793087/
https://ncbi.nlm.nih.gov/pubmed/26923598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.02.020
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