Folding of cohesin’s coiled coil is important for Scc2/4-induced association with chromosomes

Cohesin’s association with and translocation along chromosomal DNAs depend on an ATP hydrolysis cycle driving the association and subsequent release of DNA. This involves DNA being ‘clamped’ by Scc2 and ATP-dependent engagement of cohesin’s Smc1 and Smc3 head domains. Scc2’s replacement by Pds5 abro...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Petela, Naomi J, Gonzalez Llamazares, Andres, Dixon, Sarah, Hu, Bin, Lee, Byung-Gil, Metson, Jean, Seo, Heekyo, Ferrer-Harding, Antonio, Voulgaris, Menelaos, Gligoris, Thomas, Collier, James, Oh, Byung-Ha, Löwe, Jan, Nasmyth, Kim A
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2021
Teme:
Chromosomes and Gene Expression
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8279761/
https://ncbi.nlm.nih.gov/pubmed/34259632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.67268
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