Scc2 counteracts a Wapl-independent mechanism that releases cohesin from chromosomes during G1

Cohesin’s association with chromosomes is determined by loading dependent on the Scc2/4 complex and release due to Wapl. We show here that Scc2 also actively maintains cohesin on chromosomes during G1 in S. cerevisiae cells. It does so by blocking a Wapl-independent release reaction that requires op...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Srinivasan, Madhusudhan, Petela, Naomi J, Scheinost, Johanna C, Collier, James, Voulgaris, Menelaos, B Roig, Maurici, Beckouët, Frederic, Hu, Bin, Nasmyth, Kim A
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2019
Matèries:
Chromosomes and Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588348/
https://ncbi.nlm.nih.gov/pubmed/31225797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44736
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