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Scc2 counteracts a Wapl-independent mechanism that releases cohesin from chromosomes during G1
Cohesin’s association with chromosomes is determined by loading dependent on the Scc2/4 complex and release due to Wapl. We show here that Scc2 also actively maintains cohesin on chromosomes during G1 in S. cerevisiae cells. It does so by blocking a Wapl-independent release reaction that requires op...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6588348/ https://ncbi.nlm.nih.gov/pubmed/31225797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44736 |
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