Chimeric elk/mouse prion proteins in transgenic mice

Chronic wasting disease (CWD) of deer and elk is a highly communicable neurodegenerative disorder caused by prions. Investigations of CWD are hampered by slow bioassays in transgenic (Tg) mice. Towards the development of Tg mice that will be more susceptible to CWD prions, we created a series of chi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tamgüney, Gültekin, Giles, Kurt, Oehler, Abby, Johnson, Natrina L., DeArmond, Stephen J., Prusiner, Stanley B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for General Microbiology 2013
Pynciau:
Other Agents
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709613/
https://ncbi.nlm.nih.gov/pubmed/23100369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.045989-0
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