Small Molecule Agonist of Very Late Antigen-4 (VLA-4) Integrin Induces Progenitor Cell Adhesion

Activation of the integrin family of cell adhesion receptors on progenitor cells may be a viable approach to enhance the effects of stem cell-based therapies by improving cell retention and engraftment. Here, we describe the synthesis and characterization of the first small molecule agonist identifi...

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Détails bibliographiques
Auteurs principaux: Vanderslice, Peter, Biediger, Ronald J., Woodside, Darren G., Brown, Wells S., Khounlo, Sayadeth, Warier, Navin D., Gundlach, C. William, Caivano, Amy R., Bornmann, William G., Maxwell, David S., McIntyre, Bradley W., Willerson, James T., Dixon, Richard A. F.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2013
Sujets:
Cell Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707645/
https://ncbi.nlm.nih.gov/pubmed/23703610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.479634
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