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Clustering T cell GM1 Lipid Rafts Increases Cellular Resistance to Shear on Fibronectin through Changes in Integrin Affinity and Cytoskeletal Dynamics

Lipid rafts are small laterally mobile microdomains that are highly enriched in lymphocyte signaling molecules. GM1 gangliosides are a common lipid raft component and have been shown to be important in many T cell functions. The aggregation of specific GM1 lipid rafts can control many T cell activat...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Mitchell, Jason S., Brown, Wells S., Woodside, Darren G., Vanderslice, Peter, McIntyre, Bradley W.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679097/
https://ncbi.nlm.nih.gov/pubmed/19139760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2008.103
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