Wird geladen...
Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment
Fluid shear stress is a critical determinant of vascular remodeling and atherogenesis. Both integrins and the small GTPase Rho are implicated in endothelial cell responses to shear but the mechanisms are poorly understood. We now show that shear stress rapidly stimulates conformational activation of...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2001
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125600/ https://ncbi.nlm.nih.gov/pubmed/11532928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.17.4639 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|