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Matrix-specific Suppression of Integrin Activation in Shear Stress Signaling
Atherosclerotic plaque develops at sites of disturbed flow. We previously showed that flow activates endothelial cell integrins, which then bind to the subendothelial extracellular matrix (ECM), and, in cells on fibronectin or fibrinogen, trigger nuclear factor-κB activation. Additionally, fibronect...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The American Society for Cell Biology
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1635406/ https://ncbi.nlm.nih.gov/pubmed/16928957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-04-0289 |
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