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Matrix-specific Suppression of Integrin Activation in Shear Stress Signaling

Atherosclerotic plaque develops at sites of disturbed flow. We previously showed that flow activates endothelial cell integrins, which then bind to the subendothelial extracellular matrix (ECM), and, in cells on fibronectin or fibrinogen, trigger nuclear factor-κB activation. Additionally, fibronect...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Orr, A. Wayne, Ginsberg, Mark H., Shattil, Sanford J., Deckmyn, Hans, Schwartz, Martin A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The American Society for Cell Biology 2006
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635406/
https://ncbi.nlm.nih.gov/pubmed/16928957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-04-0289
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