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Matrix-specific Suppression of Integrin Activation in Shear Stress Signaling

Atherosclerotic plaque develops at sites of disturbed flow. We previously showed that flow activates endothelial cell integrins, which then bind to the subendothelial extracellular matrix (ECM), and, in cells on fibronectin or fibrinogen, trigger nuclear factor-κB activation. Additionally, fibronect...

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Detaylı Bibliyografya
Asıl Yazarlar: Orr, A. Wayne, Ginsberg, Mark H., Shattil, Sanford J., Deckmyn, Hans, Schwartz, Martin A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Cell Biology 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635406/
https://ncbi.nlm.nih.gov/pubmed/16928957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-04-0289
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