Small Molecule Agonist of Very Late Antigen-4 (VLA-4) Integrin Induces Progenitor Cell Adhesion

Activation of the integrin family of cell adhesion receptors on progenitor cells may be a viable approach to enhance the effects of stem cell-based therapies by improving cell retention and engraftment. Here, we describe the synthesis and characterization of the first small molecule agonist identifi...

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Detalhes bibliográficos
Main Authors: Vanderslice, Peter, Biediger, Ronald J., Woodside, Darren G., Brown, Wells S., Khounlo, Sayadeth, Warier, Navin D., Gundlach, C. William, Caivano, Amy R., Bornmann, William G., Maxwell, David S., McIntyre, Bradley W., Willerson, James T., Dixon, Richard A. F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707645/
https://ncbi.nlm.nih.gov/pubmed/23703610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.479634
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