Dystroglycan Function Requires Xylosyl- and Glucuronyltransferase Activities of LARGE

Posttranslational modification of alpha-dystroglycan (α-DG) by the like-acetylglucosaminyltransferase (LARGE) is required for it to function as an extracellular matrix (ECM) receptor. Mutations in the LARGE gene have been identified in congenital muscular dystrophy patients with brain abnormalities....

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Inamori, Kei-ichiro, Yoshida-Moriguchi, Takako, Hara, Yuji, Anderson, Mary E., Yu, Liping, Campbell, Kevin P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702376/
https://ncbi.nlm.nih.gov/pubmed/22223806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1214115
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky