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SGK196 Is a Glycosylation-Specific O-Mannose Kinase Required for Dystroglycan Function
Phosphorylated O-mannosyl trisaccharide [N-acetylgalactosamine-β3-N-acetylglucosamine-β4-(phosphate-6-)mannose] is required for dystroglycan to bind laminin-G domain-containing extracellular proteins with high affinity in muscle and brain. However, the enzymes that produce this structure have not be...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3848040/ https://ncbi.nlm.nih.gov/pubmed/23929950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1239951 |
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