SGK196 Is a Glycosylation-Specific O-Mannose Kinase Required for Dystroglycan Function

Phosphorylated O-mannosyl trisaccharide [N-acetylgalactosamine-β3-N-acetylglucosamine-β4-(phosphate-6-)mannose] is required for dystroglycan to bind laminin-G domain-containing extracellular proteins with high affinity in muscle and brain. However, the enzymes that produce this structure have not be...

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Autors principals: Yoshida-Moriguchi, Takako, Willer, Tobias, Anderson, Mary E., Venzke, David, Whyte, Tamieka, Muntoni, Francesco, Lee, Hane, Nelson, Stanley F, Yu, Liping, Campbell, Kevin P.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848040/
https://ncbi.nlm.nih.gov/pubmed/23929950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1239951
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