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Prion-Like Propagation of Protein Aggregation and Related Therapeutic Strategies
Many neurodegenerative diseases are characterized by the progressive accumulation of aggregated protein. Recent evidence suggests the prion-like propagation of protein misfolding underlies the spread of pathology observed in these diseases. This review traces our understanding of the mechanisms that...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3701767/ https://ncbi.nlm.nih.gov/pubmed/23801258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-013-0196-3 |
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