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Prion-like Properties of Tau Protein: The Importance of Extracellular Tau as a Therapeutic Target
Work over the past 4 years indicates that multiple proteins associated with neurodegenerative diseases, especially Tau and α-synuclein, can propagate aggregates between cells in a prion-like manner. This means that once an aggregate is formed it can escape the cell of origin, contact a connected cel...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4106306/ https://ncbi.nlm.nih.gov/pubmed/24860099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R114.549295 |
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