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Prions and Prion-like Proteins

Prions are self-replicating protein aggregates and are the primary causative factor in a number of neurological diseases in mammals. The prion protein (PrP) undergoes a conformational transformation leading to aggregation into an infectious cellular pathogen. Prion-like protein spreading and transmi...

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Detalhes bibliográficos
Autor principal: Fraser, Paul E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106303/
https://ncbi.nlm.nih.gov/pubmed/24860092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R114.583492
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