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Prions: Protein assemblies that convey biological information

Prions derived from the prion protein (PrP) were first characterized as infectious agents that transmit pathology between individuals. However, the majority of cases of neurodegeneration caused by PrP prions occur sporadically. Proteins that self-assemble as cross-beta sheet amyloids are a defining...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Sanders, David W., Kaufman, Sarah K., Holmes, Brandon B., Diamond, Marc I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748384/
https://ncbi.nlm.nih.gov/pubmed/26844828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.01.026
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