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Cellular mechanisms of protein aggregate propagation

PURPOSE OF REVIEW: New research on the mechanisms of neurodegeneration highlights parallels between prion disease pathogenesis and other, more common disorders not typically thought to be infectious. This involves propagation of protein misfolding from cell to cell by templated conformational change...

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Detalhes bibliográficos
Main Authors: Holmes, Brandon B., Diamond, Marc I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564233/
https://ncbi.nlm.nih.gov/pubmed/23108252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WCO.0b013e32835a3ee0
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