Prime-Boost Interval Matters: A Randomized Phase 1 Study to Identify the Minimum Interval Necessary to Observe the H5 DNA Influenza Vaccine Priming Effect

Background. H5 DNA priming was previously shown to improve the antibody response to influenza A(H5N1) monovalent inactivated vaccine (MIV) among individuals for whom there was a 24-week interval between prime and boost receipt. This study defines the shortest prime-boost interval associated with an...

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Библиографические подробности
Главные авторы: Ledgerwood, Julie E., Zephir, Kathryn, Hu, Zonghui, Wei, Chih-Jen, Chang, LeeJah, Enama, Mary E., Hendel, Cynthia S., Sitar, Sandra, Bailer, Robert T., Koup, Richard A., Mascola, John R., Nabel, Gary J., Graham, Barney S.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2013
Предметы:
Major Articles and Brief Reports
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699006/
https://ncbi.nlm.nih.gov/pubmed/23633407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit180
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