Prime-Boost Interval Matters: A Randomized Phase 1 Study to Identify the Minimum Interval Necessary to Observe the H5 DNA Influenza Vaccine Priming Effect

Background. H5 DNA priming was previously shown to improve the antibody response to influenza A(H5N1) monovalent inactivated vaccine (MIV) among individuals for whom there was a 24-week interval between prime and boost receipt. This study defines the shortest prime-boost interval associated with an...

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Detalhes bibliográficos
Main Authors: Ledgerwood, Julie E., Zephir, Kathryn, Hu, Zonghui, Wei, Chih-Jen, Chang, LeeJah, Enama, Mary E., Hendel, Cynthia S., Sitar, Sandra, Bailer, Robert T., Koup, Richard A., Mascola, John R., Nabel, Gary J., Graham, Barney S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699006/
https://ncbi.nlm.nih.gov/pubmed/23633407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit180
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