Characterization of the Pichia pastoris Protein-O-mannosyltransferase Gene Family

The methylotrophic yeast, Pichia pastoris , is an important organism used for the production of therapeutic proteins. However, the presence of fungal-like glycans, either N-linked or O-linked, can elicit an immune response or enable the expressed protein to bind to mannose receptors, thus reducing t...

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Main Authors: Nett, Juergen H., Cook, W. James, Chen, Ming-Tang, Davidson, Robert C., Bobrowicz, Piotr, Kett, Warren, Brevnova, Elena, Potgieter, Thomas I., Mellon, Mark T., Prinz, Bianka, Choi, Byung-Kwon, Zha, Dongxing, Burnina, Irina, Bukowski, John T., Du, Min, Wildt, Stefan, Hamilton, Stephen R.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698189/
https://ncbi.nlm.nih.gov/pubmed/23840891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068325
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