A Dual-Mode Surface Display System for the Maturation and Production of Monoclonal Antibodies in Glyco-Engineered Pichia pastoris

State-of-the-art monoclonal antibody (mAb) discovery methods that utilize surface display techniques in prokaryotic and eukaryotic cells require multiple steps of reformatting and switching of hosts to transition from display to expression. This results in a separation between antibody affinity matu...

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Hlavní autoři: Shaheen, Hussam H., Prinz, Bianka, Chen, Ming-Tang, Pavoor, Tej, Lin, Song, Houston-Cummings, Nga Rewa, Moore, Renee, Stadheim, Terrance A., Zha, Dongxing
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707868/
https://ncbi.nlm.nih.gov/pubmed/23875020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070190
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