Genetic circuitry of Survival motor neuron, the gene underlying spinal muscular atrophy

The clinical severity of the neurodegenerative disorder spinal muscular atrophy (SMA) is dependent on the levels of functional Survival Motor Neuron (SMN) protein. Consequently, current strategies for developing treatments for SMA generally focus on augmenting SMN levels. To identify additional pote...

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Detaylı Bibliyografya
Asıl Yazarlar: Sen, Anindya, Dimlich, Douglas N., Guruharsha, K. G., Kankel, Mark W., Hori, Kazuya, Yokokura, Takakazu, Brachat, Sophie, Richardson, Delwood, Loureiro, Joseph, Sivasankaran, Rajeev, Curtis, Daniel, Davidow, Lance S., Rubin, Lee L., Hart, Anne C., Van Vactor, David, Artavanis-Tsakonas, Spyros
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2013
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696827/
https://ncbi.nlm.nih.gov/pubmed/23757500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301738110
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