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Modeling spinal muscular atrophy in Drosophila links Smn to FGF signaling

Spinal muscular atrophy (SMA), a devastating neurodegenerative disorder characterized by motor neuron loss and muscle atrophy, has been linked to mutations in the Survival Motor Neuron (SMN) gene. Based on an SMA model we developed in Drosophila, which displays features that are analogous to the hum...

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Detalhes bibliográficos
Main Authors: Sen, Anindya, Yokokura, Takakazu, Kankel, Mark W., Dimlich, Douglas N., Manent, Jan, Sanyal, Subhabrata, Artavanis-Tsakonas, Spyros
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101100/
https://ncbi.nlm.nih.gov/pubmed/21300852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201004016
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