Modeling spinal muscular atrophy in Drosophila links Smn to FGF signaling

Spinal muscular atrophy (SMA), a devastating neurodegenerative disorder characterized by motor neuron loss and muscle atrophy, has been linked to mutations in the Survival Motor Neuron (SMN) gene. Based on an SMA model we developed in Drosophila, which displays features that are analogous to the hum...

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Bibliografski detalji
Glavni autori: Sen, Anindya, Yokokura, Takakazu, Kankel, Mark W., Dimlich, Douglas N., Manent, Jan, Sanyal, Subhabrata, Artavanis-Tsakonas, Spyros
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2011
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Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101100/
https://ncbi.nlm.nih.gov/pubmed/21300852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201004016
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